Delivering molecules for research

 15 Million Molecules available to order
8 Million Molecules available on stock

 Managed from enquiry to delivery
From single molecules to screening libraries of thousands of molecules

 AKosSamples  has built the trust of hundreds of customers, from multinational pharmaceutical companies to contract and university research labs across the globe. With over ten years of experience of supplying research molecules, AKosSamples has the knowledge, experience and systems to take care of the complexities of sourcing research molecules for you.

The AKosSamples custom synthesis service is able to rapidly tender requests across its growing network of chemistry laboratories to provide research molecules not otherwise available. 

Full Structure Search in iScienceSearch
 

You can do a full structure search using AKosSamples using iScienceSearch. You can type a name in the text box, and hope that the system finds a structure, or being on the safe side, use the button "Find structure for name" on the top left to create a structure from a name. You can do a substructure search using PubChem as source. You can limit the list to AKosSamples by choosing in the "Advanced Search" in the PubChem result AKos Cons... as source - it is in pull down option at the bottom.

Use iScienceSearch to search compounds on the Internet by structure. Sometimes the situation arises that you have the AKos Number, but not the structure. An easy way is to search for the AKos Number in PubChem, http://pubchem.ncbi.nlm.nih.gov/search/ or use the test version:http://akosservice.de/akossamplesservice/php/akossamplesretrievalTest4.php?IDNUMBERS=AKOS015926121 where you replace the last 9 digits.

MOBILE REAGENTS

see

www.mobilereagents.com

Larger orders and large quantities (> 250 mg) will be priced separately.

Delivery time: Compounds that are on stock can be delivered in less than 2 weeks after we have received your order. Even if the compounds are on stock it takes some time to get them through custom procedures, which are sometimes time consuming. This is the reason that it takes sometimes two weeks.

The AKosSamples Catalogue: download below as compressed SDFiles: 

Click the file name to begin download, or right click and select "Save Target As" to download the installation file.
For ftp download configure a ftp client like shown below.
You can download the zip program from http://www.7-zip.org/

Size of the database: 5.4 million compounds on stock, 7.8 million compounds in total. The compounds that are not on stock are predominantly compounds that were synthesized earlier, but are not available any longer.

We asked our chemists that do custom synthesis to add a few virtual compounds that describe there expertise. These are compounds that can be made with high confidence.

Special Offer:

Several of our suppliers offer larger collections for a very attractive price. We supply 5 mg of dry powders in vials or well-plates. Shipping cost is 150 € to Europe and 200 € to USA, of course, in the case of big order we'll send free of charge.
 

The files contain ca. 12000 structures. We also extracted the scaffolds using the KNIME Murcko node. We have added the PASS parameters to the download files. This enables you, not only to select your molecules by structure, but also by estimated biological effects (toxicities, gene expressions, etc.)

You can download the files either by clicking on the link, or using the ftp download, see below.

Symyx 07291014562D 1 1.00000 0.00000 0

10 9 0 0 0 999 V2000
-0.4071 -0.1575 0.0000 C 0 0 0 0 0 0 0 0 0
0.3054 0.2550 0.0000 N 0 0 0 0 0 0 0 0 0
-0.4071 -0.9908 0.0000 O 0 0 0 0 0 0 0 0 0
1.0179 -0.1575 0.0000 C 0 0 3 0 0 0 0 0 0
-1.1196 0.2467 0.0000 C 0 0 3 0 0 0 0 0 0
-1.8321 -0.1575 0.0000 Br 0 0 0 0 0 0 0 0 0
1.7387 0.2467 0.0000 C 0 0 0 0 0 0 0 0 0
1.0179 -0.9908 0.0000 C 0 0 0 0 0 0 0 0 0
0.8054 0.6342 0.0000 C 0 0 0 0 0 0 0 0 0
-1.1196 1.0717 0.0000 C 0 0 0 0 0 0 0 0 0
2 1 1 0 0 0
3 1 2 0 0 0
4 2 1 0 0 0
5 1 1 0 0 0
5 6 1 4 0 0
7 4 1 0 0 0
8 4 1 0 0 0
9 4 1 0 0 0
10 5 1 0 0 0
M END
>  <AKOS_NUMBER>
AKOS000100100
>  <MOLWEIGHT>
208.09616
>  <MOLFORMULA>
C7 H14 Br N O
>  <INCHIKEY>
ASGVEEBOYNWWJR-UHFFFAOYSA-N
>  <INCHI>
InChI=1S/C7H14BrNO/c1-5(8)6(10)9-7(2,3)4/h5H,1-4H3,(H,9,10)
>  <SMILES>
CC(C(=O)NC(C)(C)C)Br
>  <MOLECULE_URL>
http://akosservice.de/akossamplesservice/php/akossamplesretrieval.php?IDNUMBERS=AKOS000100100
>  <CATALOGUE_INFORMATION>
AKOS000100100 1G (Stock Building Block) 470 EUR
AKOS000100100 2G (Stock Building Block) 740 EUR
AKOS000100100 3G (Stock Building Block) 940 EUR
AKOS000100100 5G (Stock Building Block) 1220 EUR
AKOS000100100 7G (Stock Building Block) 1300 EUR
AKOS000100100 10G (Stock Building Block) 1500 EUR
AKOS000100100 12G (Stock Building Block) 1560 EUR
AKOS000100100 25G (Stock Building Block) 2340 EUR
AKOS000100100  (Stock Screening Sample)
AKOS000100100  (Stock Building Block)
AKOS000100100  (Non Stock Can be Resynthesised)
AKOS000100100  (Non Stock Custom Synthesis) 

$$$$

If you wish to provide a link from an AKOS_NUMBER to our molecule url from your database you can create a view using the SQL below. This will provide the latest sample type data (Building Block, Screening etc.) and price information if available directly from our sample database.

This SQL assumes that your molecule table is called AKOS_MOLTABLE which contains a column name AKOS_NUMBER, you should change these accordingly. The statement was created for and tested on an ORACLE database.

CREATE OR REPLACE FORCE VIEW "AKOS_VIEW" ("AKOS_NUMBER", "MOL_URL") AS
SELECT  AKOS_NUMBER,  'http://akosservice.de/akossamplesservice/php/akossamplesretrieval.php?IDNUMBERS=' || AKOS_NUMBER
FROM AKOS_MOLTABLE
ORDER BY AKOS_NUMBER;
SHOW ERRORS;

InChI:

We added the InChI name(http://www.iupac.org/inchi/) and key (http://www.iupac.org/inchi/release102.html) to the SDFiles. The InChI Name was developed first, but this can be quite long. The InChI code was developed so search engines can index it. This is shorter and also unique.

We also have in the InChI code fairly short unique description of the structure. You can use Accelrys Draw (free-of-charge for academia and private use) to generate structures from InChI names and vice versa.

We were one of the first suppliers using this code. We have acquired the software from Xemistry GmbH. This code is very good and handles complex stereochemistry.  

Download by ftp

We recommend that you use a ftp client like FileZilla (http://filezilla-project.org/).

Host = 45629.webhosting12.1blu.de

User = ftp45629-ftp

Password = akosgmbh

In the ftp directory who will find all our compounds in several SDFiles. If you want to download only those files that contain compounds that are with very high probability on stock, go to the CAS subdirectory.

Custom Synthesis:  AKos/A1Synth can synthesize larger amounts of compounds for you which are no longer in stock (typically> 10g to 1 kg). 

Also, you can rent a chemists for a month as a full term equivalent to synthesize compounds under a secrecy agreement.

Download PASS demo version