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Tips & Tricks

How to do text searches in CWM Global Search?

We will generate two searches automatically, if you add strings to the free text search box. The one search without the quotation mark searches each string independently. The search with the quotation marks requires in most search engines that the exact string must be found.

 

 

 

 

 

 

 

 

 

 

 

Text Search
Find Structures
Name Search
 

Text Search

You can preselect your sources in CWM Global Search and get much more specific results compared to a search in Google.

Any string that you enter in the 'Synonym name or free text' box in CWM Global Search is transferred to the original web page. In CWM Global Search we enclose your query in quotation marks (" ") and also without quotation marks. If you enclose several words in quotation marks most search engines will interpret this as one string, and only give hits if exactly this string is present in the result. By default both searches are activated, if you don't want this, remove the check mark of the undesired query.

We use an example of one of our user who wanted to have quick access to a review article about cystic fibrosis where the full text should be available free on the Internet.

We selected the sources that contain open access journals and articles. The search gave immediately a number of reviews that can be read immediately.

Using Google one has to extend the query to <cystic fibrosis review open access> (we are using <> to show that this query is written without quotation marks) and one gets also a very good result. However, only the first article is really relevant, the second less. Using CWM Global Search the user gets quicker more review articles.

You can also add your own quotation marks to improve the accuracy of the query:

 

 
How to find structures for "artificial sweeteners"?

CWM Global Search was designed to find data for a compound. This question goes the other way. You start with an effect and you want to find structures for it. There are certainly databases like PubChem or MDDR that do this more structured for you. However, CWM Global Search gives you a more general pictures and helps you to find more compounds, and also more terms that describe your effect.

Text Search
Find Structures
Name Search
 

Searching for structures that can be related to some text string.

A text search for <artificial sweeteners> in Google tells you that Aspartame is the most dangerous sweetener and in another document that it is not causing cancer, but you will not find papers with many chemical structures of different sweeteners. A search with <structure of artificial sweetener> gets you better answers, but by far the best answer and the most different chemical structures are found using the following search in CWM Global Search. One of the very good results is the first hit in PubMed central giving you an overview of all the different sweet tasting proteins.

In CWM Global Search you can phrase as many queries as you want and they will be combined logical by "or".

Chemical Name Search

Text Search
Find Structures
Name Search
 

Chemical Name Search

Use it for:

bullet Type a name and quickly get a structure that can be used as template for drawing purposes. It is faster to write "morphine" instead of drawing it.
bullet A substructure search by name
bullet Finding a chemical structure if the name has errors in it, for instance an IUPAC name has a hyphen or space too much.

This service works like a Google-like search on our name index which currently holds approx. 70 million records. The service regards a chemical name like "(p-Nitrobenzoyl)acetone" internally as a sentence consisting of the three words "p", "nitrobenzoyl", and "acetone". The search for chemical names is performed by the Sphinx SQL full-text search engine.

Examples:

Search for all names that contain the word "morphine":

morphine

Search for all names that contain the words "morphine" and "methyl":

+morphine +methyl

Search for all names that contain the words "morphine" and "methyl" but not "ester" :

+morphine +methyl -ester

Search for all names that contain substring "morphine" (as a word end):

*morphine

Search for all names that contain substring "morphine" (somewhere) :

*morphine*

Search for all names that contain substring "*morphine*" and the literal string ' "3-methyl ether "':

*morphine* "3-methyl ether"

Fancy things

Search for all names that contain the word - or like in this example - a single character "m" and the word "benzene" in a maximum distance of 3 words (nice to find smaller aromatic ring systems):

"m benzene"~3

Search for all benzoic acid ethyl esters that are not substituted in para position, or in 4 position.

"benzoic acid" + "ethyl ester" -"4-" -"p-"

Search for all names that contain the words "magnesium" or "sodium" and the word "chloride":

(magnesium|sodium) +chloride

(Long) Chemical names

If you want to search for ""[2-[[(1R)-1-(benzyl)-2-keto-propyl]amino]-2-keto-ethyl]-[4-(difluoromethoxy)benzyl]-methyl-ammonium"" you have to search for it quoted:

and if you are uncertain about the correct spelling you might find it also by:

Reference: The NCI/CADD Group has released an alpha version of a chemical search name.

 

 

 

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