| How to do text searches in CWM Global
Search? We will generate two searches automatically, if you
add strings to the free text search box. The one search without the
quotation mark searches each string independently. The search with the
quotation marks requires in most search engines that the exact string
must be found.



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Text
Search You can preselect your sources in CWM Global Search and get much
more specific results compared to a search in Google.
Any string that
you enter in the 'Synonym name or free text' box in CWM Global Search is transferred to the
original web page. In CWM Global Search we enclose your query in
quotation marks (" ") and also without quotation marks. If you enclose several words in quotation
marks most search engines will interpret this as one string, and only give
hits if exactly this string is present in the result. By default both
searches are activated, if you don't want this, remove the check mark of
the undesired query.
We use an example of one of our user who wanted to
have quick access to a review article about cystic fibrosis where the
full text should be available free on the Internet.

We selected the sources that contain open access
journals and articles. The search gave immediately a number of reviews
that can be read immediately.
Using Google one has to extend the query to
<cystic fibrosis review open access> (we are using <> to show that
this query is written without quotation marks) and one gets also a very good
result. However, only the first article is really relevant, the second
less. Using CWM Global Search the user gets quicker more review
articles. You can also add your own quotation marks to improve
the accuracy of the query:
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| How to find
structures for "artificial sweeteners"?
CWM Global Search
was designed to find data for a compound. This question goes the other
way. You start with an effect and you want to find structures for it.
There are certainly databases like PubChem or MDDR that do this more
structured for you. However, CWM Global Search gives you a more general
pictures and helps you to find more compounds, and also more terms that
describe your effect.



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Searching for structures that can be related to some text string.
A text search for <artificial
sweeteners> in Google tells you that Aspartame is the most dangerous
sweetener and in another document that it is not causing cancer, but you
will not find papers with many chemical structures of different
sweeteners. A search with <structure of artificial sweetener> gets you
better answers, but by far the best answer and the most different
chemical structures are found using the following search in CWM Global
Search. One of the very good results is the first hit in PubMed central
giving you an overview of all the different sweet tasting proteins.

In CWM Global Search you can phrase as many
queries as you want and they will be combined logical by "or". |
| Chemical Name Search



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Chemical Name Search
Use it for:
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Type a name and quickly get a structure that can be used as
template for drawing purposes. It is faster to write "morphine"
instead of drawing it. |
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A substructure search by name |
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Finding a chemical structure if the name has errors in it,
for instance an IUPAC name has a hyphen or space too much. |
This service works like a
Google-like search on our name index which currently
holds approx. 70 million records. The service regards a
chemical name like "(p-Nitrobenzoyl)acetone"
internally as a sentence consisting of the three words "p",
"nitrobenzoyl", and "acetone".
The search for chemical names is performed by the
Sphinx SQL full-text
search engine.
Examples:
Search for all names that contain the word "morphine":
Search for all names that contain the words "morphine"
and "methyl":
Search for all names that contain the words "morphine"
and "methyl" but not "ester"
:
Search for all names that contain substring "morphine"
(as a word end):
Search for all names that contain substring "morphine"
(somewhere) :
Search for all names that contain substring "*morphine*"
and the literal string ' "3-methyl
ether "':
*morphine* "3-methyl
ether"
Search for all names that contain the word - or
like in this example - a single character "m"
and the word "benzene"
in a maximum distance of 3 words (nice to find
smaller aromatic ring systems):
"m benzene"~3
Search for all benzoic
acid ethyl esters that are not substituted
in para position, or in 4 position.
"benzoic acid" + "ethyl ester" -"4-" -"p-"
Search for all names that contain the words "magnesium"
or "sodium" and the
word "chloride":
(magnesium|sodium)
+chloride
If you want to search for ""[2-[[(1R)-1-(benzyl)-2-keto-propyl]amino]-2-keto-ethyl]-[4-(difluoromethoxy)benzyl]-methyl-ammonium""
you have to search for it quoted:
and if you are uncertain about the correct
spelling you might find it also by:
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Reference:
The
NCI/CADD Group has released an alpha version of a chemical search name.
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