Assay Explorer

Do you need to 

• develop templates for capturing data?
• capture varied data from disparate sources?
• display data in a plate layout?
• respond to changes in the experimental setup?
• make decisions which candidates should go to further screening?
• Are you tired of finding out that you can't compare data because you don't know under which conditions they were measured?

Capture, Analyze, Report,and Manage Biological Information in One Flexible System

Back in 1995 MDL concentrated on developing tools for biologists. These were software tools for developers and not out-of-the-box applications. The consulting group of MDL implemented successfully several biological information systems. Through this work MDL learned what  would be common at most customers and released a turn-key product, the "Assay Explorer". This is a very good way of developing products that meet the user requirements, see more about this in the section "Consulting".

ASSAY EXPLORER:

Provide an architecture for a unified biological information management system

Biologists

Define experimental variables and calculations without relying on IT
Flexible experimental set-up
Experimental analysis

IT

Extensible Data Model
Open API
Integrated VBA engine

Variable Browser

Variable Manager

Reader File Manager

Display and Analysis

The Assay Explorer is shrink-wrap application, built on top of earlier developed components.  Assay Explorer includes a default workflow and data model; however the product’s architecture allows both to be customized through a built-in Visual Basic engine.  Programmers have access to component APIs and all interface elements through the VB engine

More information you will find on the MDL home page at Symyx® Assay Explorer.

Sensen, C.W. (Ed)
Essentials of Genomics and Bioinformatics

1. Auflage - February 2002
69,- Euro / 116,- SFR
2002. XIV, 428 pages, broschure
ISBN 3-527-30541-6 - Wiley-VCH, Weinheim

From the Content
Introduction
APPLICATION DOMAINS
Genome Projects of Model Organisms
The Human Genome Project
Genetic Diseases
Pharmaceutical Bioinformatics and Drug Discovery
Agrifood and Genomics
DNA TECHNOLOGIES
Genomic Mapping and Positional Cloning, with Emphasis on Plant Science
Sequencing Technology
A DNA Microarrays Fabrication Strategy for Research Laboratories
PROTEIN TECHNOLOGIES
Two-Dimensional Gel Electrophoresis and Mass Spectroscopy for Proteomic Studies: State-of-the-Art
Proteome Analysis by Capillary Electrophoresis
BIOINFORMATICS
Using the Molecular Biology Data
Tools for DNA Technologies
Tools for Protein Technologies
Structure Information
Genomic Data Representation through Images - MAGPIE as an Example
Interaction Databases
ETHICAL, LEGAL AND SOCIAL ISSUES
Ethical Aspects of Genome Research and Banking
Genomics - Five Years from Now
INDEX
COLOR FIGURES see http://www.wiley-vch.de/books/info/3-527-30541-6

The book appeared at WILEY-VCH, and you can order it here by email.

Nicolaou, K. C. / Hanko, Rudolf / Hartwig, Wolfgang (eds.)
Handbook of Combinatorial Chemistry
Drugs, Catalysts, Materials

1. Auflage - March 2002
389,- Euro / 654,- SFR
2002. XXXI, 1114
ISBN 3-527-30509-2 - Wiley-VCH, Weinheim

This book gives a good overview of many aspects of combinatorial chemistry.

From the content
GENERAL ASPECTS
Combinatorial Chemistry in Drug Discovery
Principles of Combinatorial Chemistry
Solid and Soluble Supports for Heterogenous Systems
Linkers for Solid Phase Synthesis
Encoding Technologies
Instrumentation for Combinatorial Chemistry

SYNTHETIC CHEMISTRY
Radical Chemistry
Nucleophilic Substitution
Electrophilic Substitution
Elimination
Addition to CC Multiple Bonds Except CC Bond Formation
Addition to CX Multiple Bonds Except CO Double Bonds
Chemistry of the Carbonyl Group
Oxidation Except CC Double Bonds
Reduction Except CC Double Bonds
Cycloaddition
Main Group Organometallics
Enolates and Related Species
Transitions Metal Catalyzed Formation of Single Bonds
Metathesis and Related Processes for CC Multiple Bond Formation

SPECIAL SYNTHETIC TOPICS
Libraries of Natural Products
Synthesis of Heterocyclic Systems
Multicomponent Reactions
Combinatorial Chemistry of Oligosaccharides

DESIGN OF COMBINATORIAL LIBRARIES
Design Criteria
Estimation of Physicochemical Parameters
Virtual Libraries and Modeling
Case Study: Medicinal Chemistry

NOVEL APPLICATIONS OF COMBINATORIAL CHEMISTRY
Combinatorial Chemistry in the Fine Chemical Industry
High Throughput Process Research
Combinatorial Approaches to Catalyst Discovery
Case Study: Combinatorial Catalyst Discovery
Combinatorial Aspects of Material Research
Combinatorial Principles of Biology and Their Potential Applications to Drug Discovery

The book appeared at WILEY-VCH, and you can order it here by email.