Solid-Phase Organic REactions (SPORE)

This database of reactions of small organic molecules on solid support is designed to meet the needs of combinatorial chemistry groups. The database includes extensive data on solid-phase organic chemistry, such as information on polymeric materials, linkers, solid supports, and protecting groups. The collection is selected, abstracted, and organized by FIZ CHEMIE Berlin.

Coverage:
1963-present (1,670 references); updated quarterly

Focus:
Coupling to and from solid support; insertion of linkers and spacers; functional group protection/deprotection; modification of solid-support functionalities

Source:
Original literature, 1963-present

Latest version: 2000.4

Size:
10,000 reactions
15,700 molecules
updates add approx. 1,500 new reactions per year

Disk space:
160,000 VMS blocks (OpenVMS)
85 MB (AIX/IRIX/SOLARIS/NT)

Last Updated 20-Feb-2001