Reaction Browser

The Reaction Browser is a forms-based reaction searching application that provides sophisticated database querying and browsing options. The application is designed to tightly integrate MDL databases, corporate databases, and third-party reaction databases to assist in synthesis planning and process development. The Reaction Browser can also be linked to literature citations in your desktop applications to journal articles, patents, and other documents.

Highlights:

Assisted query building: Occasional or novice users can use the Query Assistant to guide them through the process of building queries. An expert mode is also available.

Bypass hierarchical or content differences: The Reaction Browser abstracts queries so that they can be associated with any number of database fields. The application also locates and displays customized forms when the data it retrieves demands it.

Search for transformations: Use high-level reaction classification information to search for transformations.

Perform "automatic" searches: Reaction Browser assists occasional users by combining common search options automatically to retrieve reactions from a database.

Cluster searches: You can cluster your searches according to:

• Reaction Class Broad
• Reaction Class Medium
• Reaction Class Narrow

Using the "Broad" definition, only the atoms of the reaction center are taken into consideration, "Medium" includes the alpha atoms, and "Narrow", the alpha and beta atoms.

• Solvent (by formula)
• Reagent (by formula)
• Other data fields. i.e Author

For instance you search for all methods to synthesize indoles. Using only part of the ChemInform Reaction Library gives 712 hits. Too many to look at each of them. This is not necessary and this is not what you want. You want to see the different methods. Using the broad reaction class clustering gives 279 clusters grouping the different methods.

712 Hits

Cluster by reaction class broad

279 Clusters

Cluster 1

Cluster 2

Article