Metabolite

A complete metabolism information system, Metabolite comprises a database, registration system, and browsing interface. The Metabolite Database is the only source that uses information from multiple studies to assemble structural metabolic database entries for particular parent compounds. The Metabolite Registrar enables you to create, edit, and register metabolic schemes into corporate databases. And the Metabolite Browser offers a graphical interface for searching and displaying metabolic schemes stored in either the Metabolite Database or corporate databases.

Coverage:
1901-present; updated semiannually

Focus:
Xenobiotic compounds and biotransformations (primarily medicinal drugs); indexing of path and scheme information; experimental data from in vivo and in vitro studies

Sources:
Biotransformations of Drugs (1977-1983)
Pharmacokinetics (1986-1990)
Original metabolism literature and new drug applications (1990-present)
Proceedings from International Society for the Study of Xenobiotics (ISSX) meetings

Latest version: 2000.2

Size:
8,590 parent compounds
53,373 transformations
34,537 molecules

Disk Space:
325,000 VMS blocks (OpenVMS); 160 MB (AIX/IRIX/Windows NT)

Back to Metabolism & Toxicology Databases

Last Updated 20-Feb-2001

Here is screen shot showing the metabolic pathway. 

Metabolite is also offered under DiscoveryGate. The user needs to modify the standard result screens in order to get meaningful displays from the Metabolite. Please ask for details.